PRECLINICAL STUDIES

Laying the Foundation for Breakthrough Innovations

SAFETY & TOXICOLOGY STUDIES

Genetox Safety Battery

Ames/Bacterial Mutation Test
Mouse Lymphoma Assay
In vitro Micronucleus Test
In vivo Micronucleus Test
Chromosomal Aberration Assay
In vivo Mammalian Bone Marrow Chromosomal Aberration Test

In vivo Safety Battery

Reproductive Toxicology and Carcinogenicity

In vitro ADME studies

NEUROBEHAVIOURAL AND OTHER CNS STUDIES

In vivo studies

Abuse liability (conditioned place preference)
Morris water maze
Accelerating rotarod test
Balance beam
Forced swim test
Elevated plus maze
Tail suspension test
Barnes maze (mice)

In vitro studies

In vivo Animal Efficacy Studies

IN VIVO ANIMAL EFFICACY STUDIES

In vivo animal efficacy studies are a vital step in proving the biological activity and therapeutic potential of your nutraceutical product. At KGK Science, we utilize well-established animal models to evaluate how effectively your ingredients achieve desired health outcomes, such as improving immune function, reducing inflammation, or enhancing cognitive performance. These studies provide essential data on dosage, efficacy, and potential mechanisms of action before moving into human clinical trials.

LD50 STUDIES

LD50 (Lethal Dose 50%) studies are conducted to determine the amount of a substance that leads to the death of 50% of the test population, typically in animal models. This information is crucial for assessing the safety margin of nutraceutical ingredients. KGK Science offers LD50 testing as part of a comprehensive safety evaluation, ensuring your product’s dosage is within safe limits for human consumption, minimizing risk, and meeting regulatory guidelines for market entry.

KGK Science has been delivering top-notch clinical research trials and expert regulatory support for the nutraceutical, cannabis, hemp, and psychedelic industries for over 27 years, aiding companies in bringing their products to global markets with custom trials and claim substantiation strategies.