The Orange Pill Podcast

Could improving your gut health be as simple as eating two green kiwifruits a day? In Episode 152 of The Orange Pill Podcast, we explore fascinating clinical research investigating the effects of green kiwifruit on digestive health, constipation, and overall gastrointestinal comfort. A randomized, multicenter clinical trial compared two green kiwifruits daily with psyllium fiber supplementation in people experiencing functional constipation and constipation-predominant irritable bowel syndrome (IBS-C). The findings? Kiwifruit...

What if a simple daily vitamin could help protect your cells from one of the hallmarks of aging? In Episode 151 of *The Orange Pill Podcast*, we explore findings from a four-year study within the VITAL trial investigating the effects of daily Vitamin D3 and marine omega-3 supplementation on telomere length, an important biomarker associated with cellular aging. The findings were intriguing: participants taking 2,000 IU of Vitamin D3 daily...

What if supporting healthy aging isn't just about producing more NAD+, but also understanding why our cells lose it in the first place? In Episode 150 of *The Orange Pill Podcast*, we explore the science behind NAD+, a molecule essential for cellular energy and DNA repair, and CD38, an enzyme increasingly studied for its role in age-related NAD+ decline. We take a closer look at DailyColors®, a Mediterranean-inspired blend of...

The FDA has finalized its guidance on identity and safety information for New Dietary Ingredient Notifications (NDINs). But what does this mean for the dietary supplement industry? In Episode 149 of The Orange Pill Podcast, we break down the finalized guidance, exploring the FDA's recommendations for establishing ingredient identity, presenting safety evidence, and supporting safety conclusions. With KGK Science's regulatory expertise extending to Dr. Corey Hilmas, our Chief Regulatory Officer,...

What if slowing biological aging didn't require expensive treatments or extreme lifestyle changes? In Episode 148 of The Orange Pill Podcast, we explore findings from the landmark DO-HEALTH Bio-Age trial, which followed 777 adults aged 70 and older over three years to investigate whether omega-3 fatty acids, vitamin D, and simple home exercise could influence biological aging. Using advanced epigenetic clocks, researchers found that omega-3 supplementation modestly slowed several measures...