The Orange Pill Podcast

Many wellness and nutraceutical companies believe that calling a product a dietary supplement creates a regulatory safe zone. FDA enforcement actions tell a very different story. In Episode 86 of the Orange Pill Podcast, we break down the FDA’s Bioresearch Monitoring (BIMO) Program and analyze recent FDA Warning Letters that caught sponsors, CROs, and IRBs completely off guard. This episode explains a hard regulatory truth: the FDA does not regulate...

For years, protein dominated the wellness conversation. Shakes, bars, and macro tracking became the gold standard of “healthy.” But a new movement is rapidly reshaping nutrition culture and it isn’t coming from gyms or supplement brands. It’s coming from the gut. In Episode 85 of the Orange Pill Podcast, we unpack the science behind #Fibermaxxing - the viral trend shifting attention from protein obsession to microbiome-driven health. This episode explores...

For decades, America’s food system operated in a gray zone where chemicals could quietly enter the supply chain, nutrition guidance lagged behind chronic disease, and safety was often reactive rather than preventive. That era is ending. In Episode 84 of the Orange Pill Podcast, we unpack the FDA’s newly solidified Human Foods Program (HFP) and its sweeping 2026 agenda, a regulatory blueprint that signals one of the most aggressive transformations...

For nearly a century, U.S. cosmetic regulation remained largely unchanged. That era officially ended with the passage of the Modernization of Cosmetics Regulation Act (MoCRA), and now, the FDA is racing to catch up. In Episode 83 of the Orange Pill Podcast, we unpack five major regulatory developments that signal a fundamental shift in how cosmetics are tested, labeled, and enforced in the United States. Drawing from recent FDA actions...

The world is facing a neurological emergency. Dementia cases are projected to nearly triple by 2050, and despite decades of pharmaceutical research, effective, scalable solutions remain limited. This has pushed scientists to look beyond single-target drugs and toward food-based, systems-level interventions. In Episode 82 of the Orange Pill Podcast, we explore why red beetroot is emerging as a serious scientific contender in the fight against what many researchers now call...