The Orange Pill Podcast

In this forward-looking episode, we explore the major shifts on the horizon for the dietary supplement and nutraceuticals sector in 2025. Expect a transformation driven by sustainability, science, and personalization. We cover: The rise of plant-based and functional ingredients Personalized nutrition through genomics and AI Regulatory updates on GRAS and novel ingredients The role of eco-conscious practices and clean-label demands Digital health tech and real-time supplement customization Insights into cutting-edge...

In this episode, we explore a growing issue in nutraceutical clinical research: the misuse of predicted margins to gloss over incomplete data in virtual trials. When predictive models are used in place of raw results—without validation or transparency—scientific rigor is compromised. We break down what predicted margins are, when they should (and shouldn’t) be used, and how this impacts regulatory credibility....

In this episode, we explore the FDA’s newly finalized definition of “healthy” for food labeling — a major regulatory update released in December 2024. The goal? To bring food labels in line with today’s nutrition science and help consumers make better choices. We unpack what’s changed, why it matters, and how these new rules will impact how companies across both the supplement and conventional food spaces position their products moving...

In this episode, we discuss a clinical trial conducted by KGK Science and published in the British Medical Journal of Nutrition, Prevention and Health. This randomised, double-blind, placebo-controlled study evaluated how supplementation with fava bean protein supplement impacts human strength and endurance when combined with resistance training. The findings? Fava bean protein could be a game-changer for plant-based performance. We break down the results, discuss implications for athletes and weekend...

In Episode 11 of the Orange Pill Podcast, we explore the growing trend of virtual clinical trials in the dietary supplement and conventional food industries. Learn how these innovative trial designs are making research more accessible, efficient, and data-driven—and what this shift means for the future of clinical studies. Don't miss this insightful discussion!...